Darkseid in any incarnation which features the gogo boots makes me flinch. He has been such a go-to character in the DC universe it makes me wonder if the perverse subtext of his "look" is that cross dressers will inherit the universe.
All kidding aside, I love Darkseid - he is one of my favorite villains in any universe but in the overall scheme of design he is a bit of a copout. His origins from another universe read like Greek tragedy - his epic abilities and internal struggles are really interesting to read even in the dry language of Wikipedia.
But it's the fact that his appearance never seems to match his origin - this is what drives me crazy about the designs of many comic book characters.
You don't have to look carefully to notice he is polydactyl - more than your usual number of fingers - I did this for one reason and it's a bit of a joke really. Not only is it a little bit alien, it is like the superfluous papula (third nipple) of Scaramanga (The Man With The Golden Gun) in the Bond films - it's one of those outward signs of a genetic superiority that's kind of unspoken.
I altered his facial features and leg physiology in the same way - there's an animal like streamlining and extension of the leg which indicates a more aggressive stance.
I have only one more villain redesign I will post later. And it is of course the mother of all bad costumes. I hope I did it justice.